Institute of Microbial Technology (सूक्ष्मजीव प्रौद्योगिकी संस्थान)  
A Council of Scientific & Industrial Research (वैज्ञानिक औद्योगिक अनुसंधान परिषद)
 
 
 
 
 
  About SMMRNA   About RNA   About Ligand  
  RNA plays an important role in many regulatory processes such as transcription, protein synthesis and catalysis. RNA has complex three dimensional molecular structures like proteins, which can be exploited by small molecule ligands. Relatively moderate success has been achieved by targeting ribosomal RNA (rRNA).

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  RNA is a quite versatile macromolecule and plays an important role in various cellular processes. RNA is involved in important regulatory processes such as transcription, protein function and various catalytic activities. RNA show chemical similarity to DNA, however RNA molecules can fold to form complex three dimensional...

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  The design and synthesis of novel, small therapeutic ligands has been an exciting area of pharmacology. The potentiality of macrolides (Erythromycin, Azithromycin), alkaloids (berberine, palmatine), aminoglycosides (Paromomycin, neomycin), tetracyclines (Doxycycline, Oxytetracycline), and oxazolidinones...

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  Citation :
  Mehta A1, Sonam S, Gouri I, Loharch S, Sharma DK, Parkesh R. SMMRNA: a database of small molecule modulators of RNA Nucleic Acids Res. 2014, 42(Database issue):D132-41.  
  Click here to view SMMRNA paper: http://nar.oxfordjournals.org/content/42/D1/D132.long  
 
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